Nutrição e Saúde 2

...CONTINUAÇÃO DE NUTRIÇÃO E SAÚDE 1...

ÁCIDO OXALACÉTICO:

→ É um antienvelhecedor de primeira qualidade, tão bom quanto o resveratrol.
→ Combinado com a L-Carnitina e a CoQ10 é um potente anti-cansaço mitocondrial.
→ Para se obter uma sinergia entre os três é necessária a forma sublingual.
→ A forma sublingual permite a absorção de nutrientes e nutracêuticos que são destruídos pelo suco gástrico e/ou fracamente absorvidos no trato gastrintestinal, além de evitar o efeito de primeira passagem pelo fígado.
→ O grande segredo do processo de nutrição é o processo sinergético, ou seja, é combinar nutrientes.
→ É fundamental, ao lado da CoQ10 e da L-Carnitina, no Ciclo de Krebs.
→ Está chegando agora no Brasil, sendo ainda desconhecido por muitas farmácias de manipulação. Ninguém divulga, ninguém prescreve.
→ A sinergia entre CoQ10, L-Carnitina e Ácido Oxalacético é indicada, também, (além de tudo que vimos acima) para quem sofre de fadigas crônicas e para atletas que querem melhorar o rendimento. Estudos têm demonstrado efeito positivo devastador em atletas que buscam melhorar o rendimento.

Para comprar Anti-Cansaço Mitocondrial clique no link abaixo:
http://naturaonlinetoday.loja2.com.br/category/805528-Anti-Cansaco-Mitocondrial

REFERÊNCIAS:

1-) CErretelli P, Marconi C. L-carnitine supplementation in humans. The effects on physical performance. Int J Sports Med. 1990; 11(1):1-14.

2-) Mitchell ME. Carnitine metabolism in humans subjects. II. Values of carnitine in biological fluids and tissues of "normal" subjects. Am J Clin Nutr. 1978; 31(3):481-91.

3-) Brass EP. Carnitine as ergogenic aid in health and disease. J Am Coll Nutr. 1998; 17(3):203-4.

4-) De Simone C, Famularo G, Tzantzoglou S, Trinchieri V, Moretti S, Sorice F. Carnitine depletion in peripheral blood mononuclear cells from patients with AIDS: effect of oral L-carnitine. AIDS. 1994; 8(5):655-60.

5-) Ahamad S. L-Carnitine in Dialysis Patients. Semin Dial. 2001; 14(3):209-17

6-) Loignon M, Toma E. L-Carnitine for the treatment of highly active antiretroviral therapy-related hypertriglyceridemia in HIV-infected adults. AIDS. 2001; 15(9):1194-5.

7-) Lagioia R, Scrutinio D, Mangini SG, Ricci A, Mastropasqua F, Valentini G, et al. Propionyl-L-carnitine: a new compound in the metabolic approach to the treatment of effort angina. Int J Cardiol. 1992; 34(2):167-72.

8-) Sethi R, Dhalla KS, Ganguly PK, Ferrari R, Dhalla NS. Beneficial effects of propionyl-L-carnitine on sarcolemmal changes in congestive heart failure due to myocardial infarction. Cardiovasc Res. 1999; 42(3):607-15.

9-) Bartels GL, Scholte HR. Acute myocardial ischaemia induces cardiac carnitine release in man. Eur Heart J. 1997; 18(1):84-90.

10-) Iliceto S, Scrutinio D, Bruzzi P, D'Ambrosio G, Boni L, Di Biase M, et al. Effects of L-carnitine administration on left ventricular remodeling after acute anterior myocardial infarction: the L-Carnitine Ecocardiografia Digitalizzata Infarto Miocardico (CEDIM) Trial. J Am Coll Cardiol. 1995; 26(2):380-7.

11-) Regensteiner JG, Hiatt WR. Exercise rehabilitation for patients with peripheral arterial disease. Exerc Sport Sci Rev. 1995; 23:1-24.

12-) Hou XY, Green S, Askew CD, Barker G, Green A, Walker PJ. Skeletal muscle mitochondrial ATP production rate and walking performance in peripheral arterial disease. Clin Physiol Funct Imaging. 2002; 22(3):226-32.

13-) Brevetti G, Chiariello M, Ferulano G, Policicchio A, Nevola E, Rossini A, et al. Increases in walking distance in patients with peripheral vascular disease treated with L-carnitine: a double blind, cross-over study. Circulation. 1988; 77(4):767-73.

14-) Feldman EL. Oxidative stress and diabetic neuropathy: a new understanding of an old problem. J Clin Invest. 2003; 111(4):431-3.

15-) Moretti S, Alesse E, Di Marzio L, Zazzeroni F, Ruggeri B, Marcellini S, et al. Effect of L-carnitine on human immunodeficiency virus-1 infection associated apoptosis: a pilot study. Blood. 1998; 91(10):3817-24.

16-) Lyn Patrick ND. Nutrients and HIV: part tree – n-acetylcysteine, alpha – lipoic acid, L-glutamine and L-carnitine. Altern Med Rev. 2000; 5(4):290-305.

17-) Bellinghieri G, Savica V, Mallamace A, Di Stefano C, Consolo F, Spagnoli LG, et al. Correlation between increased serum and tissue L-carnitine levels and improved muscle symptoms in hemodialyzed patients. Am J Clin Nutr. 1983; 38(4):523-31.

18-) Rauchhaus M, Coats AJ, Anker SD. The endotoxin-lipoprotein hypothesis. Lancet. 2000;356:930-3.

19-) A Kumar, H Kaur, P Devi, V Mohan - Pharmacology & therapeutics. Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-live syndrome. 2009 – Elsevier.

20-) C Carine, Yang Lichuan, Lorenzo Beverly, C Noel Y, S Andrew, S Anthony, W Elizabeth J, B M Flint. Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism. Journal of Neurochemistry. Volume 104, Issue 6, pages 1613-1621, March 2008.

21-) P Salvatore, M Silvana F, H Steven J, S Freya L, K Henry, R Franklin L. Coenzyme Q10 in cardiovascular desease. 2007, Mitochondrion.

22-) L Gian Paolo, T Luca. Clinical aspects of coenzyme Q10: Na update. Nutrition, Volume 26, Issue 3, March 2010, Pages 250–254.

23-) S Stephen, C Craig I, P Aarti A, K Jeffrey, W Michael C. The Impact of Coenzyme Q10 on Systolic Function in Patients With Chronic Heart Failure. Journal of Cardiac Failure, Volume 12, Issue 6, August 2006, Pages 464–472.

24-) Bor-Jen Lee, Yi-Chia Huang, Shu-Ju Chen, Ping-Ting Lin. Coenzyme Q10 supplementation reduces oxidative stress and increases antioxidant enzyme activity in patients with coronary artery disease. Nutrition, Volume 28, Issue 3, March 2012, Pages 250-255.

25-) Hemmi N. Bhagavan, Raj K. Chopra. Potential role of ubiquinone (coenzyme Q10) in pediatric cardiomyopathy. Clinical Nutrition, Volume 24, Issue 3, June 2005, Pages 331-338.

26-) Peter H. Langsjoen, Alena M. Langsjoen. Coenzyme Q10 in cardiovascular disease with emphasis on heart failure and myocardial ischaemia. The Asia Pacific Heart Journal, Volume 7, Issue 3, December 1998, Pages 160-168.

27-) Linggen Gao, Qunxia Mao, Jian Cao, Yutang Wang, Xianliang Zhou, Li Fan. Effects of coenzyme Q10 on vascular endothelial function in humans: A meta-analysis of randomized controlled trials. Atherosclerosis, Volume 221, Issue 2, April 2012, Pages 311-316.

28-) A.M. Soja, S.A. Mortensen. Treatment of congestive heart failure with coenzyme Q10 Illuminated by meta-analyses of clinical trials. Molecular Aspects of Medicine, Volume 18, Supplement 1, 1997, Pages 159-168.

29-) Yoshimi Nakajima, Yuta Inokuchi, Masahiro Nishi, Masamitsu Shimazawa, Kazumasa Otsubo, Hideaki Hara. Coenzyme Q10 protects retinal cells against oxidative stress in vitro and in vivo. Brain Research, Volume 1226, 21 August 2008, Pages 226-233.

30-) Gian Paolo Littarru, Peter Langsjoen. Coenzyme Q10 and statins: Biochemical and clinical implications. Mitochondrion, Volume 7, Supplement, June 2007, Pages S168-S174.

31-) Catarina M. Quinzii, Michio Hirano, Salvatore DiMauro. CoQ10 deficiency diseases in adults. Mitochondrion, Volume 7, Supplement, June 2007, Pages S122-S126.

32-) Kei Mizuno, Masaaki Tanaka, Satoshi Nozaki, Hiroshi Mizuma, Suzuka Ataka, Tsuyoshi Tahara, Tomohiro Sugino, Tomoko Shirai, Yoshitaka Kajimoto, Hirohiko Kuratsune, Osami Kajimoto, Yasuyoshi Watanabe. Antifatigue effects of coenzyme Q10 during physical fatigue. Nutrition, Volume 24, Issue 4, April 2008, Pages 293-299.

33-) Claes Hofman-Bang, Nina Rehnqvist, Karl Swedberg, Ingela Wiklund, Hans Åström. Coenzyme Q10 as an adjunctive in the treatment of chronic congestive heart failure. Journal of Cardiac Failure, Volume 1, Issue 2, March 1995, Pages 101-107.

34-) Yuk-Ling Dai, Ting-Hin Luk, Kai-Hang Yiu, Mei Wang, Pandora M.C. Yip, Stephen W.L. Lee, Sheung-Wai Li, Sidney Tam, Bonnie Fong, Chu-Pak Lau, Chung-Wah Siu, Hung-Fat Tse. Reversal of mitochondrial dysfunction by coenzyme Q10 supplement improves endothelial function in patients with ischaemic left ventricular systolic dysfunction: A randomized controlled trial. Atherosclerosis, Volume 216, Issue 2, June 2011, Pages 395-401.

35-) Enrique Teran, Isabel Hernandez, Belen Nieto, Rosio Tavara, Juan Emilio Ocampo, Andres Calle. Coenzyme Q10 supplementation during pregnancy reduces the risk of pre-eclampsia. International Journal of Gynecology & Obstetrics, Volume 105, Issue 1, April 2009, Pages 43-45.

36-) M. Keith, C.D. Mazer, P. Mikhail, F. Jeejeebhoy, F. Briet, L. Errett. Coenzyme Q10 in patients undergoing CABG: Effect of statins and nutritional supplementation. Nutrition, Metabolism and Cardiovascular Diseases, Volume 18, Issue 2, February 2008, Pages 105-111.

37-) Mikael Turunen, Jerker Olsson, Gustav Dallner. Metabolism and function of coenzyme Q10. Biochimica et Biophysica Acta (BBA) - Biomembranes, Volume 1660, Issues 1–2, 28 January 2004, Pages 171-199.

38-) Su Chi Lim, Rajmohan Lekshminarayanan, Siew Kheng Goh, Yuen Yeng Ong, Tavintharan Subramaniam, Chee Fang Sum, Choon Nam Ong, Bee Lan Lee. The effect of coenzyme Q10 on microcirculatory endothelial function of subjects with type 2 diabetes mellitus. Atherosclerosis, Volume 196, Issue 2, February 2008, Pages 966-969.

39-) Thomas Müller, Thomas Büttner, Ali-Farshad Gholipour, Wilfried Kuhn. Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease. Neuroscience Letters, Volume 341, Issue 3, 8 May 2003, Pages 201-204.

40-) G. Michael Felker. Coenzyma Q10 and Statins in Heart Failure: The Dog That Didn’t Bark. Journal of the American College of Cardiology, Volume 56, Issue 15, 5 October 2010, Pages 1205-1206.

41-) M.D. Cordero, A.M. Moreno-Fernández, M. deMiguel, P. Bonal, F. Campa, L.M. Jiménez-Jiménez, A. Ruiz-Losada, B. Sánchez-Domínguez, J.A. Sánchez Alcázar, L. Salviati, P. Navas. Coenzyme Q10 distribution in blood is altered in patients with Fibromyalgia. Clinical Biochemistry, Volume 42, Issues 7–8, May 2009, Pages 732-735.

42-) João Eduardo Salles, Valdir A. Moisés, Dirceu R. Almeida, Antonio R. Chacra, Regina S. Moisés. Myocardial dysfunction in mitochondrial diabetes treated with Coenzyme Q10. Diabetes Research and Clinical Practice, Volume 72, Issue, April 2006, Pages 100-103.

43-) Virginia E. Uhley, Stephanie G. Secontine, Michael J. Shea. The effect of pravastatin and atorvastatin on coenzyme Q10. American Heart Journal, Volume 142, Issue 2, August 2001, Pages 13A-18A.

44-) B Maria Luisa., F Giorgio. A micromethod for the estimation of oxaloacetic acid in tissues. Biochimica et Biophysica Acta, Volume 62, Issue 3, 27 August 1962, Pages 596-598.

45-) Mingzhi Song, Zailong Zhang, Chuangang Fan, Dazhi Li, Qiuhong Xu, Shiguo Zhang. A theoretical study on ethylenediamine catalyzed decarboxylation of oxaloacetic acid. Computational and Theoretical Chemistry, Volume 1022, 15 October 2013, Pages 29-34.